Results 81 to 90 of about 820,355 (255)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Effectiveness of family support-based companion video sharing to improve depression in perinatal maternity: a randomized controlled trial study protocol

Frontiers in Psychiatry
BackgroundThe importance of family support in addressing maternal anxiety and depression during pregnancy is widely recognized. However, cultural nuances and healthcare system dynamics in China call for tailored interventions for perinatal mental health.
Rantong Bao, Chenxin Yang, Ruijin Zhu, Wenzhuo Li, Yang Bai, Yang Jiang, Guoying Zhang   +6 more
doaj   +1 more source

Promoting healthy sleep in Chinese kindergarteners through a family-based intervention: protocol of the "Healthy Sleep" randomised controlled trial. [PDF]

BMC Public Health, 2023
Zhang Z, Li L, Li X, Okely A.
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Preventing alcohol use among Hispanic adolescents through a family-based intervention: The role of parent alcohol misuse. [PDF]

J Fam Psychol, 2023
Brincks A, Perrino T, Estrada Y, Prado G.   +3 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Implementation of guidelines on Family Involvement for persons with Psychotic disorders: a pragmatic cluster randomized trial. Effect on relatives’ outcomes and family interventions received

Frontiers in Psychiatry
BackgroundFamily interventions (FI) are recommended as part of the treatment for psychotic disorders, but the implementation in mental health services is generally poor.
Irene Norheim, Reidar Pedersen, Maria Lie Selle, Jan Ivar Røssberg, Jan Ivar Røssberg, Lars Hestmark, Kristin Sverdvik Heiervang, Kristin Sverdvik Heiervang, Torleif Ruud, Torleif Ruud, Vilde Maria Åsholt, Kristiane Myckland Hansson, Paul Møller, Roar Fosse, Maria Romøren   +14 more
doaj   +1 more source

Evaluating the efficacy of an online, family-based intervention to promote adolescent sexual health: a study protocol for a randomized controlled trial. [PDF]

Trials, 2023
Guilamo-Ramos V, Benzekri A, Thimm-Kaiser M.   +2 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A budget impact analysis of cost to implement a whole child health focused, family-based intervention in primary care for children with elevated BMI. [PDF]

Implement Sci Commun, 2023
Harris A, Jordan N, Carroll AJ, Graham AK, Wilson C, Wilson FA, Berkel C, Smith JD.   +7 more
europepmc   +1 more source