Results 181 to 190 of about 2,547,941 (344)
A cross-national comparative study of work demands/support, work-to-family conflict and job outcomes
, 2018 Brendan Burchell, Francis Annor
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DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
EFEKTIVITAS PELATIHAN KETERAMPILAN DASAR KONSELING UNTUK PENANGGULANGAN WORK FAMILY CONFLICT (WFC) DAN PERANCANGAN SISTEM PENYELENGGARAAN KONSELING [PDF]
, 2017 Tiffany Damitta Purnomo
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Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
The Effect of Work Family Conflict on the Job Satisfaction Moderated by Chronic Regulatory Focus
, 2019 Ade Irma Suryani +5 more
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
A study of relationship between work-family conflict and occupational stress in police personnel
Archives of Mental Health, 2016 Background: Both work and family are central to one's life but these roles do not always readily reconcile, in particular when workers are faced with major stressors in the work place and long working hours, such as in police service.
Ramya P Keerthi +2 more
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