Results 121 to 130 of about 13,930,990 (311)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

A case of ankylosing spondylitis in female siblings

open access: yesItalian Journal of Medicine
Historically, ankylosing spondylitis (AS) was thought to be more common in males than in females. However, recent research into AS epidemiology has revealed an increasing incidence of female patients.
Aigerim Abuova   +6 more
doaj   +1 more source

Keeping the roof over your head : a consumer guide to homeowners insurance (2009) [PDF]

open access: yes, 2009
"Information from Human Environmental Sciences Extension.""Family financial education."Revised 06/09 ...
Family Financial Education Extension
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Faith, Family, and Forbearance [PDF]

open access: yes, 2019
In her work entitled A Narrative of the Captivity and Restoration of Mrs. Mary Rowlandson (1682), Mary Rowlandson of the Massachusetts Bay Colony describes her experience of being captured and kept prisoner by a group of Algonquian Indians for 11 weeks ...
Ballou, Julia
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Family Medicine Symposium (FMGSS) 2023

open access: yesMcGill Journal of Medicine, 2023
Family Medicine Graduate Student Society at McGill University
doaj   +1 more source

New Family of Luminescent Tetranuclear Lanthanide-Based Germsesquioxanes: Luminescence and Temperature Sensing

open access: green, 2023
Gautier Félix≠   +10 more
openalex   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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