Results 171 to 180 of about 13,866,076 (358)

Kif26b , a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme

, 2010
Yukako Uchiyama, Masaji Sakaguchi, Takeshi Terabayashi, Toshiaki Inenaga, Shuji Inoue, Chiyoko Kobayashi, Naoko Oshima, Hiroshi Kiyonari, Naomi Nakagata, Yuya Sato, Kiyotoshi Sekiguchi, Hiroaki Miki, Eiichi Araki, Sayoko Fujimura, Satomi Tanaka, Ryuichi Nishinakamura   +15 more
openalex   +2 more sources

Structure and function of interleukin-17 family cytokines [PDF]

, 2011
Xiao-Ping Zhang, Pornpimon Angkasekwinai, Chen Dong, Hong Tang   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Navigating the Emotional Challenges of Grade School: The Influence of Early Family Strains and a Lack of Parental Responsiveness on Trajectories of Anxiety and Depressive Symptoms. [PDF]

Fam Process
Lopez M, Brock RL, James TD, Nelson JM, Espy KA, Nelson TD.   +5 more
europepmc   +1 more source

Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program [PDF]

, 2008
Georg Ehret, Alanna C. Morrison, Ashley O’Connor, Megan L. Grove, Lisa Baird, Karen Schwander, Alan B. Weder, Stephen S. Rich, D. C. Rao, Steven C. Hunt, Eric Boerwinkle, Aravinda Chakravarti   +11 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Using Queer Theory to Advance Understandings of 'Queer Caregiving' With LGBTQ+ Older Adults. [PDF]

Scand J Caring Sci
Hall S, Oswald A.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

What Is My Role? A Qualitative Study of Labor, Birth, and Postpartum Experiences of Partners. [PDF]

Nurs Health Sci
Pereda-Goikoetxea B, Fiaño-Santos M, Tomas-Riscado S, Uranga-Iturriotz M, Huitzi-Egilegor JX.   +4 more
europepmc   +1 more source

A role for OVATE FAMILY PROTEIN1 (OFP1) and OFP4 in a BLH6-KNAT7 multi-protein complex regulating secondary cell wall formation in Arabidopsis thaliana [PDF]

, 2015
Yuanyuan Liu, Carl J. Douglas
openalex   +1 more source