Results 71 to 80 of about 526,329 (302)

Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their Families. [PDF]

, 2018
IntroductionThe impact of crisaborole ointment, a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild to moderate atopic dermatitis (AD), on quality of life (QoL) was assessed in two identically designed phase 3 studies (AD-301 ...
Boguniewicz, Mark, Chamlin, Sarah L, Eichenfield, Lawrence F, Feldman, Steven R, Paller, Amy S, Silverberg, Jonathan I, Simpson, Eric L, Zane, Lee T   +7 more
core   +2 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Psychological state and needs of family member caregivers for victims of traumatic brain injury: A cross-sectional descriptive study

International Journal of Nursing Sciences, 2015
Objective: Here we evaluated the impact of varying severity of traumatic brain injury on the psychological state and demands of family caregivers. Further, we determined the most significant and least significant daily needs among family caregivers ...
Weihua Liu, Jianzhong Zhu, Jing Liu, Qing Guo   +3 more
doaj   +1 more source

Health-related quality of life and functional changes in DMD:A 12-month longitudinal cohort study [PDF]

, 2016
Family caregivers of people with amyotrophic lateral sclerosis (ALS) live stressful lives in which they spend most of their time caring for their loved ones and managing difficult situations, thereby reducing the time spent in taking care of themselves ...
Baranello, G, Barcellona, C, Berardinelli, A., Bertini, E, Bruno, C, D\u2019Amico, A, D\u2019Angelo, M. G., Distefano, M. G., La Rosa, M, Marcato, S, Mazzone, E, Mercuri, E., Messina, S, Minetti, C, Mongini, T, Morandi, L, Palmieri, Arianna, Pane, M, Pegoraro, Elena, Politano, L, Rodolico, C, Scutifero, M, Sframeli M., Mondello S, Vita G., L, Vita, E   +24 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Trends in health outcomes for family caregivers of hip‐fractured elders during the first 12 months after discharge [PDF]

, 2012
Aim.  This article reports on trends in health outcomes for family caregivers of hip‐fractured patients and the effects of social support on these outcomes. Background.
Ablitt, Argimon, Chang, Chang, Chen, Cheng, Chie, Dai, Department of Health, Liang, Liang, Lin, Lin, Lin, Lu, Macleod, Ministry of the Interior, Republic of China, Morimoto, Norton, Pezzin, Pillemer, Prior, Rigby, Saban, Schoenborn, Sherbourne, Shyu, Shyu, Shyu, Shyu, Stewart, Tseng, Weitzner, Williams, Wu, Wu   +35 more
core   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Preparing Family Caregivers to Recognize Delirium Symptoms in Older Adults After Elective Hip or Knee Arthroplasty [PDF]

, 2017
Objectives To test the feasibility of a telephone-based intervention that prepares family caregivers to recognize delirium symptoms and how to communicate their observations to healthcare providers.
Boaz, Lesley, Bull, Margaret J., Gettrust, Lynn, Greene, Maureen T., Hagle, Mary E., Holmes, Sue Baird, Maadooliat, Mehdi, Saczynski, Jane S.   +7 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Silent voices: Family caregivers' narratives of involvement in palliative care

Nursing Open, 2019
Aim To explore how family caregivers experience involvement in palliative care. Design A qualitative design with a narrative approach was used. Methods Purposive sampling and narrative interviews were conducted.
Anett Skorpen Tarberg, Marit Kvangarsnes, Torstein Hole, Morten Thronæs, Torfinn Støve Madssen, Bodil J. Landstad   +5 more
doaj   +1 more source