Results 121 to 130 of about 4,459,067 (295)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Revista de Métodos Cuantitativos para la Economía y la Empresa, 2019 Este artículo estudia por medio de los modelos lineales jerárquicos, la hipótesis de incidencia positiva que las variables de pedagogía y compromiso educativo generan sobre el desempeño académico.
Astorquiza Bustos, Bilver Adrián
doaj
Population-Development-Environment Modeling in the Philippines: A Review [PDF]
This article surveys existing forecasting models in the Philippines and discusses several promising alternatives in the process of developing a methodological modeling.
Orbeta, Aniceto Jr. C.
core
THE STUDENT LEARNING DIFFICULTY FACTOR XI CLASS BUILDING DRAWING LESSONS OF EXPERTISE BUILDING SMK NEGERI 3 YOGYAKARTA [PDF]
, 2011 This study aims at determine the influence of the most dominant factor OF learning difficulties of the students in Grade XI Subject Areas Building Drawing Building SMK Negeri 3 Yogyakarta, learning difficulties were factors include: (1) Internal ...
Yuyun Sigit Pramono, Yuyun Sigit Pramono
core
Parametrization and optimization of Gaussian non-Markovian unravelings for open quantum dynamics
, 2017 We derive a family of Gaussian non-Markovian stochastic Schr\"odinger equations for the dynamics of open quantum systems. The different unravelings correspond to different choices of squeezed coherent states, reflecting different measurement schemes on ...
Luoma, Kimmo +3 more
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source