Results 121 to 130 of about 15,064,686 (342)

Kinship, Incentives and Evolution [PDF]

We analyze how family ties affect incentives, with focus on the strategic interaction between two mutually altruistic siblings. The siblings exert effort to produce output under uncertainty, and they may transfer output to each other.
Ingela Alger, Jörgen Weibull
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The socio-economic gradient in early child outcomes: evidence from the Millennium Cohort Study [PDF]

This paper shows that there are large differences in cognitive and socio-emotional development between children from rich and poor backgrounds at the age of 3, and that this gap widens by the age of 5.
Kathy Sylva, Lorraine Dearden, Luke Sibieta   +2 more
core  

Patient/Family Education for Newly Diagnosed Pediatric Oncology Patients [PDF]

, 2016
There is a paucity of data to support evidence-based practices in the provision of patient/family education in the context of a new childhood cancer diagnosis.
Ahern, JoAnn, Barakat, Lamia P., Bhatia, Smita, Bingen, Kristin M., Bondurant, Patricia G., Cohn, Susan L., Dobrozsi, Sarah K., Haugen, Maureen, Herring, Ruth Anne, Hockenberry, Marilyn, Hooke, Mary C., Landier, Wendy, Martin, Melissa, Murphy, Kathryn, Newman, Amy R., Rodgers, Cheryl C., Ruccione, Kathleen S., Sullivan, Jeneane, Weiss, Marianne E., Withycombe, Janice, Yasui, Lise   +20 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Officer-Involved Domestic Violence: The Mediating Factors [PDF]

, 2018
Domestic and family violence has been a critical issue in contemporary society. Efforts have been made in researching the causes, effects, and mediating factors of domestic violence in relation to the workplace.
Baron, Isaac
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Book review: young British muslims: identity, culture, politics and the media [PDF]

, 2012
In Britain’s highly politicised social climate in the aftermath of the 7/7 London bombings, this book provides an in-depth understanding of British Muslim identity through migration history, family settlement, socio-economic status, religion and culture,
Sandberg, Russell
core  

P/2006 VW139: A Main-Belt Comet Born in an Asteroid Collision?

, 2012
In this paper we apply different methods to examine the possibility that a small group of 24 asteroids dynamically linked to main-belt comet P/2006 VW139, recently discovered by the Pan-STARRS1 survey telescope, shares a common physical origin.
Alberto Cellino, Bertini, Bodewits, Bojan Novaković, Bottke, Bottke, Bottke, Bowell, Brož, Capria, Carruba, Cellino, Cellino, Cheng, Dell’Oro, Durda, Everitt, Fernández, Gomes, Haghighipour, Henry H. Hsieh, Hsieh, Hsieh, Hsieh, Hsieh, Hsieh, Hsieh, Jewitt, Jewitt, Jewitt, Jewitt, Knežević, Levison, Marcus, Marzari, Marzari, Masiero, Michel, Migliorini, Milani, Milani, Milani, Milani, Milani, Morbidelli, Morbidelli, Mothé-Diniz, Nesvorný, Nesvorný, Nesvorný, Nesvorný, Nesvorný, Novaković, Novaković, Novaković, Prialnik, Schörghofer, Snodgrass, Tanga, Tsiganis, Tsiganis, Vokrouhlický, Vokrouhlický, Vokrouhlický, Vokrouhlický, Zappalà, Zappalà, Zappalà, Zappalà, Zappalà   +69 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source