Results 71 to 80 of about 1,186,710 (255)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Can reactivity to stress and family environment explain memory and executive function performance in early and middle childhood?

Trends in Psychiatry and Psychotherapy
Introduction: According to the literature, children's overall reactivity to stress is associated with their socioeconomic status and family environment.
Luciane da Rosa Piccolo, Jerusa Fumagalli de Salles, Olga Garcia Falceto, Carmen Luiza Fernandes, Rodrigo Grassi-Oliveira   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Ecological Validity of Expressed Emotion in Early Psychosis

Frontiers in Psychiatry, 2019
Expressed emotion (EE) is an aspect of the family environment that influences the course of multiple forms of psychopathology. However, there is limited research about how EE dimensions [i.e., criticism and emotional over-involvement (EOI)] are expressed
Lídia Hinojosa-Marqués, Tecelli Domínguez-Martínez, Thomas R. Kwapil, Neus Barrantes-Vidal, Neus Barrantes-Vidal, Neus Barrantes-Vidal   +5 more
doaj   +1 more source

Family in transition environment [PDF]

Socioloski pregled, 2004
The broadest frame of this paper is the question of what society in transition means for family transition, and vice versa. The term 'transition' has a meaning that is appreciated widely enough for it include the largest, deeply rooted and easily recognized changes in a society, as well as those changes which are at first glance minor, less significant
openaire   +2 more sources

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Demographic Characteristics of Minor Victims of Sexual Offenses in Romania—A Retrospective Study

Forensic Sciences
Background/Objectives: Child sexual abuse (CSA) is a serious public health and forensic issue, associated with significant psychological, psychiatric, and social consequences.
Ștefania Andrei, Daria Hemeș, Adelina Dubaș, Alina Frunză, Daniela Gabriela Andrei, Cosmina Chivu, Anna Florescu, Matei Dragodan, Albert Merfu, Bogdan Pădure, Sorin Hostiuc   +10 more
doaj   +1 more source

Post Traumatic Growth for Gestational Diabetic Patients During COVID-19: Role of Partner Supportive Communication and Family Environment

International Journal of Women's Health, 2021
Zhidan Wang,1 Alishba Hania,2 Asma Muzaffar,2 Saadia Zia2 1School of Education Science, Jiangsu Normal University, Xuzhou, 221116, People’s Republic of China; 2Department of Psychology, Institute of Southern Punjab, Multan, PakistanCorrespondence ...
Wang Z, Hania A, Muzaffar A, Zia S
doaj  

FAMILY ENVIRONMENT: THE ADAPTATION OF IDEAL FORM OF FAMILY ENVIRONMENT SCALE IN THE CULTURAL ENVIRONMENT OF LATVIA

SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference, 2017
The tool for research the family environment, Family Environment Scale (FES) which is created by Moos and Moos in Latvia wasn’t adopted, that why is important to adopt this tool in environment of Latvia, because this will be chance for specialists to use good and multidimensional tool for research of family environment.
openaire   +3 more sources