Results 171 to 180 of about 14,098,722 (307)

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Toward the HER-WELL Framework: A Qualitative Mind-Map Study of Wellness Dimensions Among Women in Saudi Arabia. [PDF]

J Multidiscip Healthc
AlNujaidi HY, Al-Rayes SA, Alumran A.
europepmc   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Support needs for chronic disease self-management among persons attending a Primary Health Care facility in Victor Khanye, Mpumalanga. [PDF]

S Afr Fam Pract (2004)
Hlongwane W, Crowley T.
europepmc   +1 more source

International Water Management Institute (IWMI): Financial Statements for December 31, 2006 with Independent Auditor's Report

, 2007
Independent auditor's report for IWMI's financial statements as of December 31, 2006 and statements of activity, statements of assets, and cashflows.
International Water Management Institute
core  

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Workplace telepressure and workplace cognitive failure among hospital financial personnel: a mediation analysis and latent profile analysis based on work-family conflict and self-regulatory fatigue. [PDF]

Front Public Health
Li Q, He X, Zhang K, Su S, Ren K, Liu Q.
europepmc   +1 more source

Family Financial Management Styles and Financial Literacy in Couples

The Proceedings of the Annual Convention of the Japanese Psychological Association
Tetsuji KAMIYA, Michiyo KATO, Rie YABUKI
openaire   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Health-seeking behaviours and sociocultural factors influencing self-management of diabetes mellitus type 2 among women: a descriptive qualitative study from Islamabad, Pakistan. [PDF]

BMJ Public Health
Majid S, Shaikh BT.
europepmc   +1 more source