Results 61 to 70 of about 30,036 (260)
Factors Associated with The Resilience of Breast Cancer Patients Undergoing Chemotherapy
Pediomaternal Nursing Journal, 2020 Introduction: The management of chemotherapy in breast cancer requires a long time and cause miscellaneous of side effects. High resilience is needed by breast cancer patients to undergo chemotherapy regularly.
Ariyani Wisudawati Nira +2 more
doaj +1 more source
, 2007 The aim of this chapter is to review issues relating to wellbeing and stress that may affect psychologists. It will discuss the causes of stress and wellbeing and the outcomes for psychologists, then set out some realistic ways in which stress can be ...
Gardner, Dianne +1 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Stress and psychological wellbeing in local humanitarian workers in Colombia working for a local non-governmental organization : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Albany, New Zealand [PDF]
, 2008 This study examined the differences in stress and psychological wellbeing in 75 local humanitarian personnel (70 females and 5 males, median age = 30.7) from "Fundacion CC", local non-governmental organisation from Medellin, Colombia, who worked either ...
Abad, Jaime
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Status quo and influencing factors of family hardiness in children with bronchiolitis obliterans
Huli yanjiu, 2022 ObjectiveTo investigate the status quo and influencing factors of family hardness in children with bronchiolitis obliterans （BO）.MethodsFrom January 1，2018，to May 31，2021，a total of 261 children with BO and their parents who were treated in a children's ...
TAN Xiaoyan +7 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source