Results 71 to 80 of about 3,774 (250)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Structural Equation Modeling of Marital Satisfaction Based on Spiritual Well-Being and Psychological Hardiness: The Mediating Role of Marital Adjustment [PDF]

open access: yesمطالعات زن و خانواده
The family is one of the Crucial societal institutions that plays a significant role in Individual growth, upbringing, and psychological well-being within society.
Mohammadreza Tamannaeifar   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Mediating Role of Psychological Hardiness in the Relationship between Attachment Style and Psychological Distress during the COVID-19 Outbreak

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2022
Aim and Background: The present study was aimed to investigating the mediating role of psychological hardiness in the relationship between attachment style and psychological distress during the outbreak of the Covid-19 virus.
Ali Mahmoudian   +3 more
doaj  

The Effect of Compassion-Focused Therapy on Resilience and Family Hardiness in Female-Headed Households [PDF]

open access: yesپژوهشنامه روانشناسی مثبت
The number of female heads of households is increasing, they are more vulnerable to the stresses brought to the family, and employment and life responsibilities are more difficult for them than for married women (Asieduet et al., 2024).
Elahe Falah Tafti   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Real-world holistic care for adult cancer survivors and their families: improved family dynamics and positive outlook

open access: yesAcademia Mental Health & Well-Being
For Pete’s Sake is a non-profit organization that provides adult cancer survivors and their families with complimentary holistic support. Families receive a 4–7-day respite experience.
Natalie Hamrick   +10 more
doaj   +1 more source

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