Results 61 to 70 of about 3,046,791 (314)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Riesgo familiar total en familias con escolares según rendimiento académico Risco familiar total em famílias com escolares conforme aproveitamento acadêmico Total family risk in families with schoolchildren according to academic performance

open access: yesAvances en Enfermería, 2009
Este artículo presenta los resultados del estudio cuyo objetivo fue establecer las diferencias en el riesgo familiar entre dos grupos de familias: con niños escolares de alto rendimiento y niños de bajo rendimiento académico en un centro educativo ...
CAROLINA LUCERO ENRÍQUEZ GUERRERO   +1 more
doaj  

Family Wellbeing and Sexual Health of Patients Receiving Treatment for Prostate Cancer

open access: yesCancer Management and Research, 2023
Carielle Joy Rio,1 Taichi Goto,1 Chao-Pin Hsiao,2 Alexander LR Ross,1 Leorey N Saligan2 1National Institute of Nursing Research, Division of Intramural Research, National Institutes of Health, Bethesda, MD, USA; 2Case Western Reserve University School of
Rio CJ   +4 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Men's health by race and ethnicity, Ohio, 2004

open access: yes, 2006
Title from PDF t.p. (viewed on Aug.
Tyner-Onyeaghor, Linda.   +1 more
core  

O Programa de Educação pelo Trabalho para a Saúde na formação profissional

open access: yesRevista Brasileira de Educação Médica
Este estudo descreve as experiências das equipes de trabalho do PET-Saúde após sua implantação na universidade entre 2009 e 2010. Trata-se de relato de experiência retrospectivo, descritivo e inovador, por possibilitar aos estudantes e profissionais a ...
Maisa Tavares de Souza Leite   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Perfil socioeconômico e demográfico e a capacidade funcional de idosos atendidos pela Estratégia Saúde da Família de Paranoá, Distrito Federal

open access: yesRevista Brasileira de Geriatria e Gerontologia
OBJETIVOS: Estabelecer o perfil socioeconômico, demográfico e funcional de idosos atendidos pela Estratégia Saúde da Família (ESF) em Paranoá, Distrito Federal, Brasil, e observar as possíveis associações entre os fatores encontrados com o nível de ...
Adriano Drummond   +1 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Letter from James Lyman on farming, profits, and family health [PDF]

open access: yes, 1959
Letter likely from James Lyman in East Hampton, Massachusetts to his brother, Reverend Horace Lyman, and his family.
Lyman Family in East Hampton, Mass.
core  

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