Results 71 to 80 of about 3,046,791 (314)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Healthcare and the homeless prepared for the Connecticut Department of Public Health.
, 2003 Title from PDF cover (viewed June 21, 2004).; " ... prepared by MATRIX Public Health Consultants, Inc. ..."--Acknowledgements.; " ... commissioned by the State of Connecticut Department of Public Health, Bureau of Community Health, Family Health Division"
MATRIX Public Health Consultants, Inc.
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Revista Latino-Americana de Enfermagem, 2006 This epidemiological and exploratory-descriptive study aimed to identify the socioeconomic and demographic features, as well as the health and disease condition of elderly people from a Family Health Program in Porto Alegre, Brazil, with the purpose of ...
Luccas Melo de Souza +2 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Implementation Science Communications, 2020 Introduction Hypertensive disorders in pregnancy result in about 76,000 maternal deaths per year worldwide. Pre-eclampsia and eclampsia cause the most deaths. Interventions for managing these disorders are available in health facilities.
Olukolade George Shobo +6 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A safe and supportive family environment for children: key components and links to child outcomes [PDF]
, 2014 Aims to understand more about the prevalence of different types of family environments in society and to explore the influence of these environments on different child outcomes. Introduction Families are the mainstay of safety and support for children.
Higgins, Daryl +3 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
, 2006 Title from cover of PDF file (viewed on Aug. 1, 2007).; "March 2006"--P.
Ohio Dept. of Health. +1 more
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