Results 91 to 100 of about 4,817,785 (305)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2020 Fan Wang,1,2 Shunying Yu,3 Rubai Zhou,1 Ruizhi Mao,1 Guoqing Zhao,1,4 Xiaoyun Guo,1 Qingqing Xu,3 Jun Chen,1 Chen Zhang,1 Yiru Fang1,5,6 1Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine ...
Wang F +9 more
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The Effect of Family History, Physical Activity, and Overweight on Type 2 Diabetes Mellitus in Elderly Iin Padang Bulan Community Health Center, Medan [PDF]
, 2018 Background: Diabetes mellitus is a global public health problem. In Indonesia, the prevalence of diabetes mellitus increased from 1.1% in 2007 to 2.1% in 2013. Prevalence of diabetes mellitus in North Sumatera was 2.3%. Medan ranked second highest with 2.
Nurmaini, N. (Nurmaini) +2 more
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Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
How young people find out about their family history of Huntington's disease [PDF]
, 2009 Family communication about adult-onset hereditary illness can be problematic, leaving some relatives inadequately informed or ignorant of their risk.
Forrest Keenan, Karen +4 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Ideal Whole Health Family Oriented Community Center [PDF]
, 2012 This paper discusses what would make up the ideal whole health family oriented community center. It looks at the history of community centers in a general manner, and it looks at three existing community centers in New Hampshire.
St. Germain, Jessica
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Family history of prostate and colorectal cancer and risk of colorectal cancer in the Women's health initiative. [PDF]
, 2017 BackgroundEvidence suggests that risk of colorectal and prostate cancer is increased among those with a family history of the same disease, particularly among first-degree relatives.
Beebe-Dimmer, Jennifer L +8 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Preventing Chronic Disease, 2010 IntroductionFamily history of certain chronic diseases is a risk factor for those diseases. We assessed demographic characteristics associated with familial risk for common diseases and whether familial risk was associated with intent to share family ...
Margaret G. Au, MBE, MS +6 more
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