Results 101 to 110 of about 4,817,785 (305)

INFLUENCE OF THE FACTOR FAMILY HISTORY ON THE RISK OF CORONARY HEART DISEASE

open access: yesЕвразийский Кардиологический Журнал, 2015
For the purpose of investigating the correlation between incidence of myocardial infarction (MI) and family history of cardiovascular disease (CVD), the study of prevalence of CVD among the first-degree relatives of patients with a known MI episode has ...
J. A. Behbudova
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Prevalence, Clinical Characteristics, and Risk Among Patients with Ischemic Heart Disease in the Young Jordanian Population

open access: yesOpen Access Emergency Medicine, 2020
Liqaa A Raffee,1 Khaled Z Alawneh,2 Rashid K Ibdah,3 Sukaina I Rawashdeh,3 Sohaib Zoghoul,4 Abdel Salam Ewais,1 Abdel-Hameed Al-Mistarehi5 1Department of Accident and Emergency Medicine, Faculty of Medicine, Jordan University of Science and Technology ...
Raffee LA   +6 more
doaj  

Role of One Month Yoga Training on Arterial Stiffness in Young Adults with Familial Hypertension: A Prospective Interventional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Family history of hypertension is an important non modifiable risk factor that may lead to development of hypertension in otherwise healthy individuals. This is reflected in altered vascular stiffness parameters in these subjects.
Yashwanth Yellanki   +5 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Evaluation of Febrile Convulsion; prevalence & clinical manifestations among children under 6 years referring to south Health Centers in Tehran on 2008 [PDF]

open access: yes
Objective: The present study was designed to evaluate the frequency & clinical manifestations of the Febrile Convulsion in children under 6 years in an Iranian sample.
آهنگرزاده, سميه   +2 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background The effects of some atherosclerotic cardiovascular disease (ASCVD) risk factors vary according to whether an individual has a family history (FHx) of premature coronary heart disease (CHD).
Roberta Florido   +8 more
doaj   +1 more source

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