Results 231 to 240 of about 12,436,746 (396)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Plasma Protein Profile Associated With a Family History of Early-Onset Coronary Heart Disease. [PDF]

open access: yesCirc Genom Precis Med
Wahrenberg A   +14 more
europepmc   +1 more source

Family history and coronary heart disease prevalence

open access: green, 2005
R. D. Kurbanov   +5 more
openalex   +1 more source

Exploring Obesity Risk Factors: Focuses on Family History of Overweight and Smoking Behaviour

open access: diamond
Cynthia Arsita   +4 more
openalex   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Risk of Malignancy Associated with a Maternal Family History of Cancer

open access: gold, 2014
Ju Liu   +5 more
openalex   +2 more sources

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