Results 81 to 90 of about 4,817,785 (305)
Cell GenomicsSummary: Type 1 diabetes (T1D) and other autoimmune diseases (AIDs) often co-occur in families. Leveraging data from 58,284 family trios in Finnish nationwide registers (FinRegistry), we identified that, of 50 parental AIDs examined, 15 were associated ...
Feiyi Wang +12 more
doaj +1 more source
, 2011 Nadia Abraibesh ’10 planned to spend the past year studying and living with family in Libya and became a witness to history as ...
Abraibesh, Nadia, \u2710
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Sons, apprentices and successors in late medieval and early modern London: the transmission of skills and work opportunities [PDF]
, 2009 Book synopsis: The existence and changing of generations in family life, business and politics was a central feature of towns as well as rural societies in earlier times. Even so, it remains understudied by urban historians of the pre-modern period. This
Harding, Vanessa
core
Two-hour postload glycemia is associated to an increased risk of NAFLD in healthy subjects with family history of type 2 diabetes: a case control study [PDF]
, 2016 Nonalcoholic fatty liver disease (NAFLD) includes steatosis and nonalcoholic steatohepatitis (NASH), which can be complicated by cirrhosis and hepatocellular carcinoma [1].
CARNOVALE, ANNA +7 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Heritability for Stroke: Essential for Taking Family History
Caspian Journal of Internal Medicine, 2020 Background: There are many well-established factors that influence the risk of stroke including blood pressure, diabetes, low socioeconomic status and smoking, however, the shared genetic resource in members of a family effect on stroke predisposition ...
Masoumeh Pourasgari, Ashraf Mohamadkhani
doaj
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Khlebosolny/Bread and Salt : A time-travelling journey to Eastern Europe (and back)
Mobile Culture Studies. The Journal, 2018 In this article, I describe a journey my sister Rebecca and I made in 2012 to Eastern Europe, part diasporic return/roots journey and part artistic residency, during which we developed artworks in the form of ritual, performative practices with bread ...
Katy, Beinart
doaj +1 more source