Altered cortical synchronization in photosensitive idiopathic generalized epilepsy
Epilepsia, EarlyView.Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto +5 more
wiley +1 more source
Persistence of electroclinical findings in an adult patient with SETD1B‐related epilepsy
Epileptic Disorders, EarlyView.
Rohan Shankar +2 more
wiley +1 more source
β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels
Epilepsia, EarlyView.β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi +8 more
wiley +1 more source
A 21-Year Diagnostic Odyssey in TBC1D24-Associated Developmental and Epileptic Encephalopathy With Favorable Response to Corpus Callosotomy: A Case Report. [PDF]
CureusPacheco-Abbud A +8 more
europepmc +1 more source
Enhancing quality of mental health service for veterans with seizures
Epilepsia, EarlyView.Abstract Psychiatric disorders are commonly identified in people with seizures (PWS). Comorbid mood, anxiety, and trauma‐ and stressor‐related disorders are highly prevalent and not consistently recognized or treated promptly. Veterans with seizures are particularly vulnerable to neuropsychiatric comorbidities, including a higher prevalence of ...
Maria Raquel Lopez +6 more
wiley +1 more source
Candidate Serum Biomarkers of Neural Injury and Neuroinflammation in Childhood Epilepsy: Comparison Between Controlled and Drug-Resistant Phenotypes. [PDF]
Children (Basel)Türay S +5 more
europepmc +1 more source
Epilepsia, EarlyView.Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n
Sophie von Brauchitsch +27 more
wiley +1 more source
Epileptic seizures temporally associated with recombinant human growth hormone therapy in children: A case series of three patients. [PDF]
SAGE Open Med Case RepNagaki S, Shichiji M, Oguni H, Osawa M.
europepmc +1 more source
Epilepsia, EarlyView.Abstract Objective Resective surgery achieves seizure freedom in approximately 60%–80% of patients with drug‐resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear.
Addison C. Cavender +15 more
wiley +1 more source