Network connectivity in primary generalized tonic-clonic seizures. [PDF]
Clin Neurophysiol, 2022 To determine EEG spatiospectral activation and connectivity in the generalized tonic-clonic seizure (GTCS) semiological subtypes.39 patients with genetic generalized epilepsy (GGE) who had GTCS (n = 58) during video-EEG monitoring were identified in the Vanderbilt Epilepsy database. GTCSs were classified as absence tonic-clonic, myoclonic tonic-clonic,
McGuinness I +3 more
europepmc +3 more sources
Eslicarbazepine‐induced severe hyponatremia resulted in generalized tonic‐clonic seizure [PDF]
Clinical Case Reports, 2021 Although eslicarbazepine is an anti‐seizure medication, it may result in seizure worsening if its use is complicated by severe hyponatremia, even long time after commencing this medication. The treatment is a replacement for another ASM.
Mhd Baraa Habib +6 more
doaj +2 more sources
The adolescent or adult with generalized tonic-clonic seizures
Annals of Indian Academy of Neurology, 2012 Primary and secondary generalized tonic-clonic seizures (GTCs) together constitute up to 50% of adolescent and adult patients with epilepsy as diagnosed by history and EEG.
Roop Gursahani, Namit Gupta
doaj +3 more sources
EEG Network Analysis in Epilepsy with Generalized Tonic–Clonic Seizures Alone [PDF]
Brain Sciences, 2022 Many contradictory theories regarding epileptogenesis in idiopathic generalized epilepsy have been proposed. This study aims to define the network that takes part in the formation of the spike-wave discharges in patients with generalized tonic–clonic ...
Dimitrios Pitetzis +6 more
doaj +2 more sources
Long‐term open‐label perampanel: Generalized tonic–clonic seizures in idiopathic generalized epilepsy [PDF]
Epilepsia Open, 2022 Objective Assess the longer‐term efficacy and safety of adjunctive perampanel (up to 12 mg/day) in patients aged ≥12 years with generalized tonic–clonic (GTC) seizures from the Open‐label Extension (OLEx) Phase of Study 332 to determine whether responses
Jacqueline A. French +7 more
doaj +2 more sources
Carbamazepine treatment of generalized tonic–clonic seizures in idiopathic generalized epilepsy [PDF]
Seizure: the Journal of the British Epilepsy Association, 2014 AbstractPurposeEvaluate the efficacy of carbamazepine in the treatment of idiopathic generalized epilepsy (IGE).MethodThe response of five patients with IGE, who experienced primarily generalized tonic–clonic seizures which were refractory to multiple antiepileptic drugs, is reported.ResultsCarbamazepine controlled multiple seizure types and did not ...
Maromi Nei, Scott Mintzer
exaly +3 more sources
Sexual dysfunction in male patients with idiopathic generalized tonic clonic seizures [PDF]
Annals of Indian Academy of Neurology, 2021 Background: Epilepsy is the second most common neurological disorder, and it may have a significant effect on sexual functions in epileptic patients. Materials and Methods: Sexual dysfunctions were assessed in 146 male patients suffering from generalized
Rajendra Kumar Sureka +3 more
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Abnormal static and dynamic functional network connectivity of the whole-brain in children with generalized tonic-clonic seizures [PDF]
Frontiers in Neuroscience, 2023 Yongxin Li
exaly +2 more sources
Model for cascading failures in functional networks: application to epileptic patients with generalized tonic-clonic seizures [PDF]
Journal of Integrative Neuroscience, 2019 The dynamic process of epilepsy is modeled as a cascading failure model in functional networks derived from graph theory. The aim is to test whether cascading failure identified from functional magnetic resonance imaging data could simulate epileptic ...
Ming Ke, Li Cao, Guangyao Liu
doaj +1 more source
Valproic Acid versus Lamotrigine as First-line Monotherapy in Newly Diagnosed Idiopathic Generalized Tonic –Clonic Seizures in Adults – A Randomized Controlled Trial [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Idiopathic Generalized Tonic-Clonic Seizures (GTCS) are frequently encountered in adults. Their successful control is necessary to improve the quality of life of these patients.
VISHAL PRAKASH GIRI +5 more
doaj +1 more source