Results 31 to 40 of about 24,565 (251)
Seizures induced in electroconvulsive therapy as a human epilepsy model: A comparative case study
Epilepsia Open, 2021 Objective Standardized investigation of epileptic seizures and the postictal state may contribute to a better understanding of ictal and postictal phenomena.
Julia C. M. Pottkämper +4 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
An Observational Study on Clinico-Etiological Profile of Neonatal Seizures
GAIMS Journal of Medical SciencesBackground: Neonatal seizures are the most common neurological emergencies encountered in newborns. Neonatal seizures are poorly classified, under-recognized and often difficult to treat.
Pragya Punj +2 more
doaj +1 more source
Carbamazepine Therapy and Long-Term Prognosis of Epileptic Children
Pediatric Neurology Briefs, 1989 The long term prognosis in 90 children with partial or generalized tonic-clonic seizures treated with CBZ has been evaluated in the Department of Pediatrics, Kyoto University, Kyoto, Japan.
J Gordon Millichap
doaj +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
A Case of Tuberculous Meningitis with Tuberculoma in Nonimmunocompromised Immigrant
Case Reports in Pulmonology, 2016 We present a case of tuberculous (TB) meningitis in nonimmunocompromised immigrant worker who initially presented with headache and later with generalized tonic clonic seizures and disseminated tuberculosis.
Parth Rali, Hammad Arshad, Eric Bihler
doaj +1 more source
Neurologic Complications of Cat-Scratch Disease
Pediatric Neurology Briefs, 1992 An 8 year-old girl hospitalized with cat-scratch disease and recurrent generalized tonic-clonic seizures is reported from the Department of Pediatrics, Children’s Hospital, The Ohio State University, Columbus, OH.
J Gordon Millichap
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou +6 more
wiley +1 more source