Results 61 to 70 of about 4,767,344 (305)

The housing pathways of lesbian and gay youth and intergenerational family relations: a Southern European perspective

open access: yesHousing Studies, 2020
Against the heteronormativity of the increasing field of studies around intergenerational family relations within asset-based welfare systems, the paper analyses the housing pathways of lesbian and gay young people, focusing on family intergenerational ...
Cesare Di Feliciantonio   +1 more
semanticscholar   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Elderly in the state of co-residence in a town in State Bahia, Brazil

open access: yesO Mundo da Saúde, 2015
This study aims to describe the socioeconomic characteristics of the elderly and the level of individual and collective satis- faction in the structural and emotional aspects of family cohabitation. This is a cross-sectional, descriptive and exploratory
Saulo Sacramento Meira   +4 more
doaj  

Assessing the Role of Family Structure in Racial/Ethnic Residential Isolation

open access: yesSocial Sciences, 2018
Fifty years after the passage of the Fair Housing Act, racial/ethnic residential segregation and discrimination persist in the housing market. In 2018, the National Fair Housing Alliance reported that the third and fifth largest discrimination complaints
Colleen E. Wynn, Samantha Friedman
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

An absence of rights: Homeless families and social housing marketisation in Ireland

open access: yesAdministration, 2018
This paper discusses the outcomes of a participatory research process with homeless parents living in Dublin-based emergency accommodation, during which a critical appraisal of a range of government schemes was coconstructed.
Hearne Rory, Murphy Mary
doaj   +1 more source

An Energy and Water Resource Demand Estimation Model for Multi-Family Housing Complexes in Korea

open access: yes, 2012
This paper proposes and develops a residential energy and resource consumption estimation model in the context of multi-family residential housing in Korea using a multi-layer perceptron (MLP) neural network.
Dongjun Suh, Seongju Chang
semanticscholar   +1 more source

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