Results 71 to 80 of about 1,207,506 (312)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Housing systems in the Global South

open access: yesPlaNext, 2021
This paper addresses the problem of accessing decent and affordable housing in the Global South, where the housing need is, in general, more problematic than in the Global North.
Alireza Vaziri Zadeh   +2 more
doaj  

Risk and return within the single-family housing market [PDF]

open access: yes
The trade-off between risk and return in equity markets is well established. This paper examines the existence of the same trade-off in the single-family housing market.
Richard P. Voith, Theodore M. Crone
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Aging, Moving, and Housing Wealth [PDF]

open access: yes
We have described the relationship between family attributes and moving, and between moving and change in housing wealth. Moving is often associated with retirement and with precipitating shocks like the death of a spouse or by other changes in marital ...
David A. Wise, Steven F. Venti
core  

America’s Working Families [PDF]

open access: yes, 2006
[Excerpt] Working families throughout America are increasingly being squeezed—they are working longer today to pay for middle-class living than they had to 25 years ago.
AFL-CIO
core   +1 more source

Dynamic housing expenditures and household welfare [PDF]

open access: yes, 2009
In this paper we develop a measure of current "expenditures" on housing services for owner-occupiers. Having such a measure is important for measuring the relative welfare of households, especially when comparing renters and owners and for measuring ...
Blow, L., Nesheim, L.
core   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

Housing, family and children: Some of the issues in the transitional period [PDF]

open access: yesUrbani Izziv, 1995
The author deals with the process of transition in the multy-family housing sector particularly with regard to the family and children. She contends that the transitional period had a great effect on the rented sector and thus also affected potential ...
Srna Mandič
doaj  

The Impact of the Housing Crash on Family Wealth [PDF]

open access: yes, 2008
This paper extrapolates from data from the 2004 Survey of Consumer Finance to project household wealth, by wealth quintile, in 2009 under three alternative scenarios.
David Rosnick, Dean Baker
core  

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