Results 101 to 110 of about 5,602,429 (258)

Intervención Familiar Preventiva en Programas Colaboradores del SENAME: La Perspectiva del Profesional Preventive Family Intervention in Collaborating Programs of SENAME: The Worker's Perspective

open access: yesPsykhe, 2008
Se aborda la caracterización del usuario y concepción de la intervención, desde la perspectiva de psicólogos y trabajadores sociales de 6 Programas de Intervención Familiar colaboradores del Servicio Nacional de Menores.
Esteban Gómez, Ana María Haz
doaj  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Happy Family Kitchen: A Community-based Research For Enhancing Family Communication And Well-being In Hong Kong

open access: yes, 2016
Urban families worldwide are often characterized by busy working lives which leave little time for family gatherings and communication. The Happy Family Kitchen project, which emphasized cooking and dining with family members, was conducted in a deprived
Wan, NTA   +7 more
core   +1 more source

Crosswalk between HRSD and MADRS outcomes for rTMS in patients with depression

open access: yesBMJ Mental Health
Background The Hamilton Rating Scale for Depression (HRSD) and the Montgomery-Åsberg Depression Rating Scale (MADRS) are the two most common clinician-rated scales to quantify depression symptom change in repetitive transcranial magnetic stimulation ...
Xiao Chen   +6 more
doaj   +1 more source

The family as a resource for improving patient and family functioning after traumatic brain injury: A descriptive nonrandomized feasibility study of a family-centered intervention

open access: yesCogent Medicine, 2019
The aim of this study was to address feasibility aspects of a multidisciplinary, family-centered rehabilitation intervention for persons with traumatic brain injury and their family.
Mari S. Rasmussen   +4 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Effectiveness of family metacognitive training in mothers with psychosis and their adolescent children: a multicenter study protocol

open access: yesFrontiers in Psychology
BackgroundMore than half of women with psychosis take care of their children despite the difficulties caused by the disease. Additionally, these kids have a higher risk of developing a mental health disorder. However, no interventions have been developed
Susana Ochoa   +49 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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