Results 81 to 90 of about 5,602,429 (258)

Family Intervention in The Problem of Maternal Death

open access: yesHumaniora, 2018
In 2015, the maternal mortality rate in Bima was recorded as 3 cases per 1,000 births, equivalent to 300 maternal deaths per 100,000 births. Although this number is low, it is much higher than the zero mortality rate set by the Sustainable Development ...
Atik Triratnawati, Anis Izdiha
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Kaupapa Māori wellbeing framework: the basis for whānau violence prevention and intervention [PDF]

open access: yes, 2014
With Māori over-represented in family violence statistics as both victims and perpetrators, this paper identifies some key considerations for implementing violence prevention and intervention initiatives.
Terry Dobbs, Moana Eruera
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Calls to roll out family intervention programme.

open access: yes, 2016
Children were better prepared for starting school and parents made wiser use of the health service as a result of a family intervention programme trialled in a disadvantaged part of Dublin......
Shanahan, Catherine
core  

The UK Government’s Troubled Families Programme: Delivering Social Justice?

open access: yesSocial Inclusion, 2018
This article examines and reviews the evidence surrounding the UK Government’s Troubled Families Programme (TFP), a flagship social policy launched in 2011, following riots in towns and cities across England. The programme aims to work with over 500,000 ‘
Stephen Crossley
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Family violence across the life cycle [PDF]

open access: yes, 2014
Aims to address clinical questions that general practitioners (GPs) may have in identifying and responding to patients experiencing family violence. Background Family violence covers a range of abuse including child abuse and neglect, intimate partner ...
Kelsey Hegarty   +3 more
core  

The Effectiveness of Psychological Interventions for Families of Children With Type 1 Diabetes on Caregiver and Child Functioning: A Systematic Review and Meta‐Analysis

open access: yesJournal of Diabetes
Background Research suggests that the wellbeing of caregivers of children with Type 1 Diabetes can influence child health outcomes. Therefore, the aim was to conduct a systematic review and meta‐analysis to estimate the effect of psychological ...
Katherine E. Wakelin   +8 more
doaj   +1 more source

Internet-based psychoeducation and support programme for relatives of young people with early psychosis: results of the first German-language intervention

open access: yesFrontiers in Psychiatry
BackgroundInternational clinical guidelines recommend Family Interventions (FIs) especially for families of people at early stages of psychosis. The German S3 treatment guideline for schizophrenia gives FIs the highest level of clinical recommendation ...
Mar Rus-Calafell   +12 more
doaj   +1 more source

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