Results 191 to 200 of about 4,182,366 (344)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Tips for teaching skin procedures to family medicine residents. [PDF]

MedEdPublish (2016)
Motamedi F, Rivet C, Wooltorton E.
europepmc   +1 more source

Family Medicine Forum 2008 makes the top 10

, 2008
Cal Gutkin
openalex  

The role of the Department of Family Medicine at OFS

, 1995
G.J. Pistorius, M V van Vuuren, LA Hiemstra   +2 more
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Hepatitis C Virus Treatment Outcomes Using a Family Medicine Interdisciplinary Team. [PDF]

Ann Fam Med
Hull M.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Storylines of family medicine XII: family medicine and the healthcare system

Family Medicine and Community Health
Rebecca S Etz, Kurt C Stange, Kendall M Campbell, William L Miller, Thomas Bodenheimer, Robert L Ferrer, Roger Strasser, Joshua Freeman, William B Ventres, Leslie A Stone, Jeannette E South-Paul, Aerial R Petty, Hima Ekanadham, Marianna Kong, Sharon C M Reece, John M Westfall   +15 more
doaj   +1 more source

Family medicine: The missing mother specialty of MBBS. [PDF]

J Family Med Prim Care
Kumar R.
europepmc   +1 more source

How do family medicine residents choose an anticoagulation regimen for patients with nonvalvular atrial fibrillation? [PDF]

, 2017
Payam Yazdan-Ashoori, Zardasht Oqab, William F. McIntyre, Kieran L. Quinn, Erik van Oosten, Wilma M. Hopman, Adrián Baranchuk   +6 more
openalex   +1 more source