Results 71 to 80 of about 1,924,278 (308)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Evaluation of Training Family Health Center Practice in Family Medicine Residency Education

open access: yesJournal of Medical Education and Family Medicine
Objective: Tertiary hospitals offer advanced health services, including chronic disease management, whereas primary health care centers focus on services such as pregnancy follow-up, child care, vaccination, and periodic health screenings.
Nesibe Derya Bayhan, Abdulkadir Kaya
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

EFFECT OF FAMILY MEDICINE TRAINING PROGRAM ON HOUSE OFFICER'S PERCEPTION OF FAMILY MEDICINE SPECIALTY IN EGYPT [PDF]

open access: yesEuromediterranean Biomedical Journal
The Egypt's commitment to universal health coverage has emphasized the growing need for well-trained family physicians. Nonetheless, Family Medicine remains underrated as a career choice for medical students.
Asmaa Ahmed Sayed
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A Multielement Community Medicine Curriculum for the Family Medicine Clerkship

open access: yesMedEdPORTAL, 2016
Introduction Many medical schools provide opportunities for students to learn about health disparities, social determinants of health, and the role physicians play in promoting health equity.
Rebecca Bernstein   +2 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

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