Results 81 to 90 of about 2,265,049 (313)
Journal of General and Family Medicine, 2023 Background Despite the increasing need for primary care physicians (PCPs) around the world, few physicians choose it as a career. PCPs who can find meaning and enjoyment in their work can be role models for medical students and professionals, which may ...
Yu Yamamoto +3 more
doaj +1 more source
Family medicine in Japan [PDF]
British Journal of General Practice, 2009 If you are passionate about primary care then it is always uplifting to meet people who feel the same. The argument for a structured primary care system in Japan has been ongoing for some time but it is only in the last few years that it is gathering momentum. Indeed, from a distance one might wonder why on earth Japan needs to change anything?
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Rakel's Textbook of Family Medicine
South African Family Practice, 2007 No abstract available.
Arina Schlemmer
doaj +1 more source
THE "FAMILY" OF FAMILY MEDICINE [PDF]
The Annals of Family Medicine, 2013 Most of us joined the American Academy of Family Physicians (AAFP) as active members upon graduation from our residency training programs. During our careers, our memberships in other family medicine organization have likely evolved. However, the alphabet soup of abbreviations of our varied family medicine organizations can be a bit confusing and the ...
M. Tuggy +9 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Becoming a family medicine specialist
South African Family Practice, 2008 No abstract available.
Pierre J.T. de Villiers
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Next steps for the East, Central and Southern Africa College of Family Physicians (ECSA-CFP)
African Journal of Primary Health Care & Family MedicineNo abstract available.
Innocent K. Besigye +4 more
doaj +1 more source