Results 101 to 110 of about 4,197,886 (264)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Addressing Barriers to Breast Cancer Screening: Where to Intervene to Increase Mammogram Completion Rates [PDF]

, 2017
Methods: Study sought to determine if an intervention would aid in increasing mammogram screening rates in the Jefferson Family Medicine Associates practice.https://jdc.jefferson.edu/patientsafetyposters/1061/thumbnail ...
LaPorta, MD, Jennifer, Leshner, MD, Amy, Love, MD, Gillian, McClowry, MD, Robert J., McIntosh, MD, Lionel, McManus, MD, Patrick, Rague, MD, Allison, Sizemore, MD, Daniel, Talley, MD, Elizabeth Mackie, Thesing, MD, Claire   +9 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Family physician hospitalists: the good and the bad

McGill Journal of Medicine, 2020
A hospitalist is the most responsible physician for inpatient care without the responsibility for care post discharge. In Canada, the majority of hospitalists are family physicians which raises concerns in the context of a shortage of family physicians ...
Satya Rashi Khare
doaj  

An evaluation of palliative care education in the specialist training programme in family medicine [PDF]

, 2010
Aim: The study aimed to evaluate the teaching in palliative care (PC) provided during the Specialist Training Programme in Family Medicine (STPFM) in Malta.
Abela, Jurgen C., Mallia, Pierre
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Are people in Tehran prepared for the family physician program?

International Journal of Preventive Medicine, 2014
Background: Upon successful experiences of family physician program in the rural regions, Iranian Ministry of Health and Medical Education (MOHME) made a decision to expand this program to urban areas.
Azam Majidi, Nina Loori, Khandan Shahandeh, Ensiyeh Jamshidi, Reza Majdzadeh   +4 more
doaj  

Perception of medical students about family medicine in Karachi, Pakistan: Medical students’ perception about family medicine

Journal of Family Medicine and Primary Care
Objectives: To assess the perceptions of medical students about Family Medicine (FM) as a career choice and to examine if exposure to FM in undergraduate medical curriculum is associated with a positive perception of FM.
Munazza Asad, Unab I. Khan, Anum Arshad
doaj   +1 more source

Development of Guidelines for Refugee Screening at CMMC Family Medicine Residency, Lewiston, Maine [PDF]

, 2016
Lewiston Maine has the second highest number of refugees in the state of Maine, with 191 total intakes in 2015. Refugee populations face unique health concerns, and providing care for refugees requires education and development of a specialized skill ...
Hayes, Catherine
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source