Results 71 to 80 of about 4,197,886 (264)

Recycling the evidence: Different approaches to the reanalysis of elite life histories [PDF]

open access: yes, 2008
The chapter considers the re-analysis of a specific data set, the life histories of a select group of pioneers of geriatric medicine collected by Professor Margot Jefferys' in 1991.
Bornat, Joanna, Wilson, Gail
core  

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance [PDF]

open access: yes, 2016
Sialyltransferases are a family of 20 gene products in mice and humans that transfer sialic acid from its activated precursor, CMP-sialic acid, to the terminus of glycoprotein and glycolipid acceptors.
Aja, Susan   +7 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

EFFECT OF FAMILY MEDICINE TRAINING PROGRAM ON HOUSE OFFICER'S PERCEPTION OF FAMILY MEDICINE SPECIALTY IN EGYPT [PDF]

open access: yesEuromediterranean Biomedical Journal
The Egypt's commitment to universal health coverage has emphasized the growing need for well-trained family physicians. Nonetheless, Family Medicine remains underrated as a career choice for medical students.
Asmaa Ahmed Sayed
doaj   +1 more source

Department of Family Medicine and Public Health Sciences 2006 Annual Report: Addressing Health Challenges in Michigan [PDF]

open access: yes, 2007
2006 annual report includes: Greetings from the Chair, Maryjean Schenk; Introducing New Faculty; Full-time affiliate and Voluntary Faculty; In Memoriam: John B.
Wayne State University School of Medicine, Department of Family Medicine and Public Health Sciences
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Four “teachable moments” for “planetary health” or how to integrate sustainable healthcare topics into clinical courses in family medicine for undergraduate medical students

open access: yesGMS Journal for Medical Education
This article discusses the integration of planetary health and sustainable healthcare into family medicine education, focusing on undergraduate medical training.
Telemachos Hatziisaak   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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