Results 121 to 130 of about 5,195,770 (298)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Noss Family Musical Novelty Company

open access: yes, 1880
This is a cabinet photograph of the Noss family musicians, which includes the father and mother, their six children, and some of their instruments. Also known as the "Noss Jollities of Musical Comedy," the family resided in New Brighton, Pennsylvania ...
Gootee Family
core   +1 more source

'Our family came to be with this name'

open access: yesNordisk Tidskrift för Socioonomastik
The article focuses on surname choices among families in Denmark, seeking to add a new perspective by proposing that the choices and narratives of surnames contain information about and reflect family identity formation as well as family and gender ...
Katrine Kehlet Bechsgaard
doaj   +1 more source

L-R: Maggie [last name unknown], Jack Deir and Pearl [last name unknown]

open access: yes, 1936
Taken at Bowring Park in St. John's.Cataloguer's title.Jack Deir married Kathleen (Forbes) Deir, daughter of Dr. C.A. Forbes and Irene (Matthews) Forbes, June 11, 1936.
Forbes Family
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Ball Family coat of arms, undated

open access: yes, 1910
Postcard featuring two coats of arms for the Ball family. The front left section of the postcard features a Ball family coat of arms with a lion on top of a shield with three stars.
Ball family
core   +2 more sources

McRae family papers

open access: yes
This collection contains biographical, family and business documents for members of six generations of the family of Thomas C.
McRae family
core   +1 more source

Name Tag

open access: yes
A small name tag with the name Tsutom Takenaga.The collection documents the personal life and business records of the Ishibashi family; one of the pioneer Japanese American farming families on the Rancho Palos Verdes Peninsula in Los Angeles, California ...
Ishibashi Family
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Desarrollo de un instrumento evaluativo del aprovechamiento docente en estudiantes del quinto semestre académico de la carrera de Medicina

open access: yesRevista Habanera de Ciencias Médicas, 2014
Introducción: para valorar en qué medida los estudiantes logran cumplir los objetivos a final de la asignatura Propedéutica Clínica se requiere crear un instrumento basado en un examen teórico y práctico que aborde las habilidades a lograr.
Miguel Ángel Blanco Aspiazú   +11 more
doaj  

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