Results 121 to 130 of about 4,363,731 (298)

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Sevillana

open access: yes, 1895
D majorAll brillanteA Seville, belles Senoras, On brave les frimas8205Published by Heugel & Cie Au Ménestrel, 2bis.
Massenet, Jules, 1842-1912   +3 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Neuberg Family Collection 1839-1892

open access: yes
The collection contains documents of the Neuberg (née Neumögen) family, including certificate permitting the family members to change their last names, certificate pertaining to Bernhard Neuberg's completion of medical school and beginning of his ...
Neuberg (Family), Neumögen (Family)
core  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

A névelemek sorrendje és kulturális kongruenciája a Borsszem Jankó zsidó figuráinak névanyagában a 20. század első felében. [Order and cultural congruence of the elements in personal names for Jewish characters appearing in a Hungarian humour magazine entitled Borsszem Jankó in the first half of the 20th century]

open access: yesNévtani Értesítő, 2013
This study is based on previous research, which examined the name stock referring to Jewish characters occurring in a Hungarian humour magazine entitled Borsszem Jankó between 1901 and 1937.
Németh, Luca Anna
doaj  

Business cards of Hendricks-Tobias Family Companies from the Hendricks-Tobias Business Correspondence, undated, 1882, 1889

open access: yes
Business cards originally found in Box 2, Folder 66. The business cards include companies bearing the Hendricks and Tobias family names, are operated by either family, or from companies doing business with Hendricks & Brothers.Digital ...
Hendricks family, Tobias family
core  

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