Results 131 to 140 of about 1,854,409 (340)
An evaluation of DGA classifiers [PDF]
, 2018 Domain Generation Algorithms (DGAs) are a popular technique used by contemporary malware for command-and-control (C&C) purposes. Such malware utilizes DGAs to create a set of domain names that, when resolved, provide information necessary to establish a ...
Choudhary, Chhaya +5 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Development of the family names classification in Miljevci
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2007 This article presents the development of the classification of family names in Miljevci starting from the late 17th century, when the first family names were documented in the registers, up to the ones that appear by the end of the 19th century. It shows
Ankica Čilaš Šimpraga
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Névtani Értesítő, 2014 Spatial distribution of proper names – similarly to that of common nouns – is a natural consequence of language change; as a result, the geography of personal (especially family) names has recently become an important field of study in international and ...
N. Fodor, János
doaj
The Purpose of Building Buddha Statue in Sejong - City and Family Name of Baekje
, 2016 Do hack Lee
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source