Results 51 to 60 of about 478,626 (316)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Family and Physicians' Views of Surrogate Decision-Making: The Roles and How to Choose

open access: yes, 1996
Physicians and family members were compared on the roles played in surrogate decision-making and their views as to how choices should be made by surrogate decision-makers.
Silberfeld, Michel   +3 more
core   +1 more source

Investment in family medicine to improve health outcomes in sub-Saharan Africa

open access: yesAfrican Journal of Primary Health Care & Family Medicine
Family physicians (FPs), as educators, capacity builders and clinical governance leaders of primary care (PC) teams, work to make them more effective and responsive to the needs of their patients.
Sunanda C. Ray   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Association Between Sleep Duration and Health Outcome in Elderly Taiwanese

open access: yesInternational Journal of Gerontology, 2011
Background: The aim was to assess the relationship between sleep duration and self-rated health outcome in the elderly Taiwanese. Methods: The data were drawn from the National Survey on Knowledge, Attitude, and Practice of Health Promotion 2002 (HPKAP ...
Meng-Ting Tsou
doaj   +1 more source

“Better than having no evaluation done”: a pilot project to conduct remote asylum evaluations for clients in a migrant encampment in Mexico

open access: yesBMC Health Services Research, 2021
Background Asylum evaluations are highly specialized medico-legal encounters to collect physical or mental health evidence for use in immigration proceedings.
Ranit Mishori   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Some actual trends in Medical Education

open access: yesRed U, 2012
Sincethe "Flexneriane" revolution 100 years ago, many attempts have been made to change how medicine is taught, and many new general tendencies in education have appeared.
Carlos Alberto Brailovsky   +1 more
doaj   +1 more source

Medicalization of poverty: a call to action for America’s healthcare workforce

open access: yesFamily Medicine and Community Health, 2022
As a social determinant of health, poverty has been medicalised in such a way that interventions to address it have fallen on the shoulders of healthcare systems and healthcare professionals to reduce health inequities as opposed to creating and ...
Danielle D Jones
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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