Results 71 to 80 of about 2,481,408 (365)

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

The Effectiveness of Counseling Through Vasectomy Module in North Kolaka, Indonesia [PDF]

open access: yes, 2017
The main problem faced nowadays is the low participation of men in terms of implementation of the Family Planning Program. The figures for family planning in Indonesia only demonstrate a high rate on contraception use in women not in men. The Strategy to
Askrening, A. (Askrening)   +1 more
core   +2 more sources

Empowering Online Adult Educators: Integrating Artificial Intelligence for Enhanced Instructional Strategies

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores how artificial intelligence (AI) can support online adult learning by aligning with Knowles’ four principles of andragogy: involvement, experience, problem‐centeredness, and relevance. Three activities were analyzed using a comparative case study (CCS) method.
Xi Lin, Steve W. Schmidt
wiley   +1 more source

Upregulation of miR-205 induces CHN1 expression, which is associated with the aggressive behaviour of cervical cancer cells and correlated with lymph node metastasis

open access: yesBMC Cancer, 2020
Background Cervical cancer is the leading cause of cancer-related death in women worldwide. However, the mechanisms mediating the development and progression of cervical cancer are unclear.
Jianbing Liu   +9 more
doaj   +1 more source

Family planning in Nigeria

open access: yesAcademic Medicine, 1969
The Family Planning Council of Nigeria which is a voluntary organization sponsored by the National Council of Women of Nigeria is involved in the family planning programs in Nigeria working in conjuction with the Department of Community Health of the Lagos University College of Medicine. The Family Planning Council was inaugurated in 1964.
openaire   +3 more sources

Institutional Policies on Artificial Intelligence in Higher Education: Frameworks and Best Practices for Faculty

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores institutional policies on artificial intelligence (AI) in higher education. As AI tools become increasingly utilized in academia—from research and teaching to assessment and student support—institutions face growing pressure to establish clear, ethical, and practical guidelines to help guide faculty.
Lauren Azevedo   +3 more
wiley   +1 more source

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