Results 141 to 150 of about 14,065,685 (383)

Reviving Full-Service Family Practice in British Columbia [PDF]

, 2011
Describes innovative operational reforms made in the province's fee-for-service system to improve quality of care and reduce costs, including incentive payments for chronic disease management and enhanced training.
Garey Mazowita, William Cavers
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Chronic pain in family practice: research and insights. [PDF]

Can Fam Physician, 2023
Fraser S.
europepmc   +1 more source

Family practice - meanings for modern times [PDF]

, 2010
Allen, Amanda Howe, Bailey, Benzies, Blankfield, Guthrie, Howe, Launer, Phillips, Reay   +9 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Higher interest to continue COVID-19 practice recommendations in non-pandemic times among German GPs with better crisis leadership skills (egePan study)

BMC Health Services Research
Background The German College of General Practitioners and Family Physicians (DEGAM) issued a COVID-19 guideline with eleven recommendations to support primary care services during the pandemic.
Benjamin Aretz, Yelda Krumpholtz, Simon Kugai, Nicola Amarell, Manuela Schmidt, Birgitta Weltermann   +5 more
doaj   +1 more source

A review of published research in the South African Family Practice - A clarion call to action. [PDF]

S Afr Fam Pract (2004), 2023
Von Pressentin KB, Kaswa R, Murphy S, Nair A.   +3 more
europepmc   +1 more source

1369: Working together — Achieving more an advanced nursing practice project for children with cardiology problems and their families [PDF]

, 2007
Gaby Stoffel
openalex   +1 more source

Ethical issues in family practice [PDF]

, 2001
The Raison d'etre principles in biomedical ethics have clearly become what are referred to as the four principles. These can be summarized as the Principles of Beneficence, Nonmaleficence, Respect for Autonomy and Justice.
Mallia, Pierre
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source