Results 131 to 140 of about 9,149,435 (259)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
BMC GeriatricsIntroduction After being diagnosed with dementia, patients need a medical professional to empathetically address their fears and get initial questions answered.
Flora-Marie Hegerath +4 more
doaj +1 more source
Scope of work and the future of family practice. [PDF]
Can Fam Physician, 2022 Lemire F, Slade S.
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Family medicine : present and future
, 2013 Contents: Future prospects of the College - Pierre Mallia; The contemporary College and Council - Jason J Bonnici; Immersion pulmonary oedema in a scuba diver - Mario Saliba; eHealth and mHealth - bridging gaps in health care - Martina FalzonThe ...
Mallia, Pierre +2 more
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Brief interventions for suicidal ideation in primary care: a systematic review
BMC Primary CareBackground General practitioners (GPs) play a crucial role in assessing and diagnosing suicidal ideation, often acting as the first person of contact for individuals with mental health concerns. Given the time constraints faced by primary care providers,
Puya Younesi +6 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Genealogical Family History in Aotearoa-New Zealand: From Community of Practice to Transdisciplinary Academic Discourse? [PDF]
, 2008 Genealogical Family Historians conduct research in order to reconstruct genealogical families, through the application of a rigorous methodology: weighing the evidence for placing each individual in a family group, linking family groups of the past and ...
Brown, Margaret Mary Selman
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
A review of published research in the South African Family Practice - A clarion call to action. [PDF]
S Afr Fam Pract (2004), 2023 Von Pressentin KB +3 more
europepmc +1 more source