Results 141 to 150 of about 8,832,657 (301)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Brief interventions for suicidal ideation in primary care: a systematic review

BMC Primary Care
Background General practitioners (GPs) play a crucial role in assessing and diagnosing suicidal ideation, often acting as the first person of contact for individuals with mental health concerns. Given the time constraints faced by primary care providers,
Puya Younesi, Carolin Haas, Tobias Dreischulte, Andrea Schmitt, Jochen Gensichen, Karoline Lukaschek, for the POKAL-Group   +6 more
doaj   +1 more source

A review of published research in the South African Family Practice - A clarion call to action. [PDF]

S Afr Fam Pract (2004), 2023
Von Pressentin KB, Kaswa R, Murphy S, Nair A.   +3 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Physicians' professionalism from the patients' perspective: a qualitative study at a single-family practice in Saudi Arabia. [PDF]

BMC Med Ethics, 2023
AlFaris E, Irfan F, Abouammoh N, Zakaria N, Ahmed AM, Kasule O, Aldosari DM, AlSahli NA, Alshibani MG, Ponnamperuma G.   +9 more
europepmc   +1 more source

A Comprehensive Exploration of Ayurvedic Medicine: The ancient history, principles of Indian traditional medicine and integration into modern medicine: ‘EDI – Equity, Diversity and Inclusion’ based project

Introduction: Ayurvedic medicine, an ancient system of healthcare that originated in India over 5,000 years ago, has significantly influenced modern medicine in various ways.
Default Account, Family Practice Resident
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Trail Tips for Residency: A Reflection of Residency Through Film

Introduction: Reflective practice is becoming more widely recognized as an important part of medical training. Recently, several qualitative studies have suggested reflection through film as a potential method to promote a strong reflective practice ...
Erickson, Jacquie, Default Account, Family Practice Resident   +1 more
core   +1 more source

Family practice

Academic Medicine, 1976
openaire   +3 more sources

Community-acquired pneumonia - use of chest x-rays for diagnosis in family practice. [PDF]

BMC Prim Care, 2022
Eilat-Tsanani S, Kasher C, Levine-Kremer H.   +2 more
europepmc   +1 more source