Results 161 to 170 of about 4,362,522 (358)

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Natural history of abdominal pain in family practice: Longitudinal study of electronic medical record data in southwestern Ontario. [PDF]

open access: yesCan Fam Physician, 2023
Freeman TR   +7 more
europepmc   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Ethical issues in family practice [PDF]

open access: yes, 2001
The Raison d'etre principles in biomedical ethics have clearly become what are referred to as the four principles. These can be summarized as the Principles of Beneficence, Nonmaleficence, Respect for Autonomy and Justice.
Mallia, Pierre
core  

Self-reported acceptability and feasibility of a multimodal intervention to reduce antibiotic prescriptions for urinary tract infections in primary care: a process evaluation of the RedAres trial among general practitioners and medical practice assistants

open access: yesBMC Health Services Research
Background Urinary tract infections are common and lead to frequent and inappropriate antibiotic prescribing in primary care. The RedAres randomized controlled trial has shown to reduce second-line antibiotic use for urinary tract infections through a ...
Angela Schuster   +13 more
doaj   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

open access: yesFEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian   +4 more
wiley   +1 more source

The Role of Motivational Persistence and Resilience Over the Well-being Changes Registered in Time [PDF]

open access: yes, 2015
The present study investigates the interaction between personal characteristics that are considered nowadays strengths used to face difficult events or transition period.
Bostan, Cristina Maria
core  

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