Results 201 to 210 of about 8,832,657 (301)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Prevalence and Predictors of Common Sleep Disorders among the Elderly in a Major Family Practice Center in Saudi Arabia. [PDF]

open access: yesSaudi J Med Med Sci
AlHaqwi AI   +8 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

A Review of Pathways for Integration of Medical Abortion Care into the Primary Care Setting and Proposal of Strategies for Sustainable Abortion Care in the Community of Fort St John.

open access: yes
Background With most abortions occurring in the first trimester and delays in presentation relating to referral of patients from primary care providers integration of abortion care into primary care practices is integral to ameliorating access.
Hatcher, Jessica   +1 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

A ‘Primary Care’ Focused Summary and Appraisal of the Canadian Network for Mood and Anxiety (CANMAT) 2016 Guidelines for the Pharmacological Management of Adults with Major Depressive Disorder

open access: yes
Objective: The role of primary care physicians in management of depression isexpanding, and there is a notable gap in family physician’s knowledge and comfort inmanaging pharmacotherapy.
Default Account, Family Practice Resident   +1 more
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

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