Results 221 to 230 of about 1,216,251 (316)

Establishing a standing patient advisory board in family practice research: A qualitative evaluation from patients' and researchers' perspectives. [PDF]

Health Expect
Engler J, Engler F, Gerber M, Brosse F, Voigt K, Mergenthal K.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Gender Disparities in Adverse Events Resulting From Low-Value Practices in Family Practice in Spain: A Retrospective Cohort Study. [PDF]

Int J Public Health
Mira JJ, Carratala-Munuera C, Vicente MA, Astier-Peña MP, García-Torres D, Soriano C, Sánchez-García A, Chilet-Rosell E, Gil-Guillén VF, López-Pineda A, Pérez-Jover V.   +10 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Retraction: Unicentric Castleman Disease With Systemic Symptoms: A Rare Case From Family Practice. [PDF]

Cureus
Aljuaid AK, Iskandar MN, Almalki AA, Alsuqayh KS, Almufarrih YA, Alosaimi SG, Aljamaan LF, Aldaihani SF, Alghamdi SA, Alaamree MA, Fageeh LM, Almagrafi SA, Al Halbub AY, Alghamdi ZS, Al-Hawaj F.   +14 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Erratum to: Discussing weight loss opportunistically and effectively in family practice: a qualitative study of clinical interactions using conversation analysis in UK family practice. [PDF]

Fam Pract, 2021
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Retraction: Intraosseous Calcaneal Lipoma Misdiagnosed as Plantar Fasciitis: An Orthopedic Case From Family Practice. [PDF]

Cureus
Alnooh AM, Al Furaikh BF, Alaithan AM, Halawani AK, Al-Khalifah MF, Abu Zahirah MO, Alhasani MH, Asiri AA, Alrashid AH, Alfaqih EH, Khair MA, Naiser SS, Alkamel YS, Al Mohammed AA, Al-Hawaj F.   +14 more
europepmc   +1 more source