Results 81 to 90 of about 1,504,132 (259)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Behind the Sadness of Teen Girls: A Retrospective Survey Analysis Amidst the COVID-19 Crisis of 2021

open access: yesAdolescents
(1) Background: Adolescent girls have increasingly faced mental health challenges. We examined prevalence trends and associated risk factors for depression among adolescent girls.
Onur Baser   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Nonmarital Childbearing and Family Structure Among Asian Americans: The Role of Socioeconomic Status, Ethnicity, and Immigration

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences
This study examines how maternal education shapes nonmarital childbearing and family structure among Asian Americans compared with non-Hispanic Whites.
Fumiya Uchikoshi, Airan Liu
doaj   +1 more source

Unraveling the sorrows of aging: Prevalence and determinants of geriatric depression in a developing country

open access: yesInternational Journal of Noncommunicable Diseases
Background and Objectives: Globally, depression is one of the leading causes of disability and economic burden in health care. India with its ever-increasing large elderly population faces a major challenge of geriatric depression.
Praveen Kumar Tasir   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Erken Cumhuriyet Türkiye’sinde Ailenin Yeniden İnşası

open access: yesİçtimaiyat
Erken Cumhuriyet Dönemi, Türkiye’de aile kurumunun bir toplumsal yapı olmanın ötesinde, devletin modernleşme, laikleşme ve vatandaşlık inşası politikalarının taşıyıcısı olarak yeniden kurgulandığı bir dönüşüm sürecidir.
Harun Aydın
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Demografik Dönüşüm ve Aile: Türkiye Nüfus Dinamiklerinin Aile Yapısına ve Sosyal Politikaya Etkileri

open access: yesİçtimaiyat
Günümüzde demografik dönüşüm, nüfus göstergelerindeki değişimlerin ötesine geçerek aile kurumunun işleyişi ile biçimsel yapısını dönüştürmekte ve sosyal politika alanında belirgin kırılmalara yol açmaktadır.
Faruk Selahattin Yolcu
doaj   +1 more source

Structural biology of the TGFβ family

open access: yesExperimental Biology and Medicine, 2019
The transforming growth factor beta (TGFβ) signaling pathway orchestrates a wide breadth of biological processes, ranging from bone development to reproduction. Given this, there has been a surge of interest from the drug development industry to modulate the pathway – at several points.
Erich J Goebel   +3 more
openaire   +3 more sources

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