Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Salāmat-i ijtimā̒ī, 2016 Background and Objective: According to the high prevalence of running away from home by the teenager girls in Iran and the negative consequences of this issue in the society, this study aimed to investigate the phenomenon of running away from home by ...
Maryam Falahatpishe +3 more
doaj
Bowlby's five therapeutic tasks: bringing them up to date for children
BJPsych BulletinBowlby remained attached to his psychoanalytic roots and conceptualised treatment in terms of one-to-one relationships, albeit acknowledging the need for a family formulation.
Simon R. Wilkinson
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Mechanisms of inequitable access to parkinson’s disease care: a critical interpretive synthesis
International Journal for Equity in HealthBackground Parkinson’s disease (PD) is a leading cause of neurological disability among older adults, with an age-standardized global prevalence in 2021 of 139/100,000 and projected to increase by 112% by 2050.
Sharon Koehn +7 more
doaj +1 more source
The Efficacy of Cognitive Behavioral Group-Therapy Alone and plus Family Psycho-Education on the Treatment of Major Depression Disorder Symptoms in Females [PDF]
, 2012 : Background & Aims: Major depression is one of the common psychiatric disorders imposing negative effects on patients and their families. There are several treatment methods for depression.
Solati Dehkordi K., Mobasheri M.,
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Music Therapy Is Associated With Family Perception of More Spiritual Support and Decreased Breathing Problems in Cancer Patients Receiving Hospice Care [PDF]
, 2015 Context Music therapy is a common discretionary service offered within hospice; however, there are critical gaps in understanding the effects of music therapy on hospice quality indicators, such as family satisfaction with care. Objectives The purpose
Burns, Debra S. +4 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The effectiveness of the satir approach-based counseling on the parenting sense of competence in adolescent mothers [PDF]
Preventive Care in Nursing and Midwifery JournalBackground: Pregnancy in adolescents is an important health issue influencing the family and society. The use of various counseling approaches can greatly affect increasing knowledge and skills, how to control emotions, and playing adult roles ...
Masoumeh Hasani +3 more
doaj +1 more source
Effectiveness of blood pressure control in a small community [PDF]
, 1989 The aim of this study was to examine the degree of control of blood pressure with respect to individuals on anti-hypertensive drug therapy attending a Health Centre for repeat prescription.
Cacciottolo, Joseph M., Galea, Wilfred
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