Results 101 to 110 of about 7,249,926 (299)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Momentos marcantes na construção da mudança em terapia familiar

open access: yesPsicologia: Teoria e Pesquisa
Assumindo as contribuições construcionistas sociais, esse estudo visa compreender o processo de produção de sentidos sobre a mudança em terapia familiar.
Emerson F. Rasera, Carla Guanaes
doaj   +1 more source

Who seeks couple and family therapy in Turkey? A descriptive analysis from the MFT-PRN

open access: yes
Despite the growing global reach of Marriage and Family Therapy (MFT), empirical knowledge of who seeks systemic therapy remains largely confined to Western, Educated, Industrialized, Rich, and Democratic (WEIRD) societies.
Gurmen, M. Selenga
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Analysis of Interactional Pathology in Families of Women with Borderline Personality Disorder Based on Interviews with Family Therapists

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2017
Aim and Background: The purpose of this study was to assess interactional pathologies among couples consisting of a woman with borderline personality disorder based on interviews with family therapists.
رضوان هویدافر   +4 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Famílias em vulnerabilidade social: rastreamento de termos utilizados por terapeutas de família

open access: yesPsicologia: Teoria e Pesquisa
Este estudo investigou se os termos "famílias em situação de risco", "famílias pobres", "famílias de camadas populares" e "famílias de baixa renda" podem referir-se ao conceito de "famílias em vulnerabilidade social", quando utilizados por terapeutas de ...
Laíssa Eschiletti Prati   +2 more
doaj   +1 more source

Brief Strategic Family Therapy Treatment for Behavior Problem Youth

open access: yes, 2015
This chapter reviews the nearly forty-year history of the Brief Strategic Family Therapy (BSFT) approach to treating adolescent problem behaviors. BSFT was developed in the mid 1970s as a response to the increased number of Cuban immigrant adolescents in
C. Hendricks Brown   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy