Results 121 to 130 of about 1,289,589 (309)

Famílias em vulnerabilidade social: rastreamento de termos utilizados por terapeutas de família

open access: yesPsicologia: Teoria e Pesquisa
Este estudo investigou se os termos "famílias em situação de risco", "famílias pobres", "famílias de camadas populares" e "famílias de baixa renda" podem referir-se ao conceito de "famílias em vulnerabilidade social", quando utilizados por terapeutas de ...
Laíssa Eschiletti Prati   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Who seeks couple and family therapy in Turkey? A descriptive analysis from the MFT-PRN

open access: yes
Despite the growing global reach of Marriage and Family Therapy (MFT), empirical knowledge of who seeks systemic therapy remains largely confined to Western, Educated, Industrialized, Rich, and Democratic (WEIRD) societies.
Gurmen, M. Selenga
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Family-focused cognitive behaviour therapy versus psycho-education for chronic fatigue syndrome in 11- to 18-year-olds: a randomized controlled treatment trial

open access: yes, 2010
Background - Only one previous randomized controlled trial (RCT) has examined the efficacy of cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) in children.
Deary, V.   +7 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Client satisfaction survey of in-home family therapy [PDF]

open access: yes, 2001
Plan BA pilot test of a client satisfaction survey was conducted in a private agency providing in-home family therapy in west central Wisconsin. The family’s names of the clients were obtained from the agency’s closed client files.
Juleff, Donna
core  

Perceptions of professional needs, practice patterns and critical issues facing family therapy trainers and supervisors

open access: yes, 1986
The field of family therapy has grown dramatically in the past decade. However, the field's training and supervision subsystems have lagged developmentally compared to the advancement of clinical methodologies.
Saba, George W, Liddle, Howard A
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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