Results 111 to 120 of about 1,289,589 (309)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Fathers in family therapy: Lessons from research
, 2014 Treatment outcome research has shown that for 2/3 to 3/4 of cases family therapy is an effective intervention for child focused problems. One factor that has consistently been shown to enhance the effectiveness of family therapy is father involvement ...
Carr, Alan
core +1 more source
Brief Strategic Family Therapy Treatment for Behavior Problem Youth
, 2015 This chapter reviews the nearly forty-year history of the Brief Strategic Family Therapy (BSFT) approach to treating adolescent problem behaviors. BSFT was developed in the mid 1970s as a response to the increased number of Cuban immigrant adolescents in
C. Hendricks Brown +9 more
core +1 more source
Taḥqīqāt-i ̒Ulūm-i Raftārī, 2017 Aim and Background: The purpose of this study was to assess interactional pathologies among couples consisting of a woman with borderline personality disorder based on interviews with family therapists.
رضوان هویدافر +4 more
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
ARE TRUSTWORTHINESS AND FAIRNESS ENOUGH? CONTEXTUAL FAMILY THERAPY AND THE GOOD FAMILY
, 1997 The moral dimension of family therapy theory and practice has received increasing attention in recent years. Boszormenyi‐Nagy was among the first to see that family therapy and moral questions are inseparable. His focus on relational ethics has helped us
Fowers, Blaine J, Wenger, Andrew
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Bullying girls - Changes after brief strategic family therapy: A randomized, prospective, controlled trial with one-year follow-up [PDF]
, 2005 Background: Many girls bully others. They are conspicuous because of their risk-taking behavior, increased anger, problematic interpersonal relationships and poor quality of life.
Loew, Thomas +16 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Fostering respect as the therapeutic basis of healthy family and couple relationships [PDF]
, 2001 Plan BThis work proposes fostering respect as the therapeutic basis for creating a healthy ecology of all human systems ranging from the individual, to the couple, family, community and beyond.
Thesing, Charles T.
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source