Results 61 to 70 of about 9,981,389 (290)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2014 Contents: President’s address at the MMCFD graduation of vocational trainees, 25 March 2014 - Pierre Mallia; MMCFD Graduation Photos 25 March 2014The mission of the Journal of the Malta College of Family Doctors (JMCFD) is to deliver accurate ...
Mallia, Pierre +2 more
core
The conceptual foundations of traditions and value relations in the Russian family
Вестник Тамбовского университета. Серия: Гуманитарные наукиImportance. Society is witnessing a shift in models of family relations, a growing popularity of interests outside the family, and a deepening problem of intergenerational understanding.
T. E. Bezruchenko
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Journal of the Malta College of Family Doctors : volume 5 : issue 3 [PDF]
, 2016 MALLIA, P. - Graduation, specialisation and future initiatives -- GRECH, A., AXIAK, S., & GERADA, C. - The interphase between family medicine and mental health -- PULLICINO, G., PAVIA, J., ZINTILIS, S., FRANCALANZA, S., SCIORTINO, P., & SCIORTINO, P. -
Mallia, Pierre +1 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Corporate values guiding the world's largest family-owned businesses: A comparison with non-family firms [PDF]
This paper analyzes formally stated corporate values, a key topic of concern in the field of family businesses. More specifically, the study aims to contribute to the literature by enabling a deeper understanding of the differences and similarities of ...
Tapies, Josep, Ceja, Lucia
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Историческая этнологияThe article is devoted to the study of the system of traditional family values among the Turkic-speaking peoples living in the lowland part of Dagestan.
Madina B. Gimbatova
doaj +1 more source