Results 81 to 90 of about 5,761,106 (281)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

How to evaluate health-related quality of life and its association with medication adherence in pulmonary tuberculosis – designing a prospective observational study in South Africa

Frontiers in Pharmacology, 2016
Introduction: Health-related quality of life (HRQOL) has become an important measure to identify and shape effective and patient-relevant healthcare interventions innovations through outcomes.
Tanja Kastien-Hilka, Tanja Kastien-Hilka, Tanja Kastien-Hilka, Bernd Rosenkranz, Bernd Rosenkranz, Bryan Bennett, Edina Sinanovic, Matthias Schwenkglenks, Matthias Schwenkglenks, Matthias Schwenkglenks   +9 more
doaj   +1 more source

Do family values and reproductive health knowledge influence reproductive health-promoting behaviors in married women? A cross-sectional survey. [PDF]

Korean J Women Health Nurs, 2022
Yun SJ, Kim HY.
europepmc   +1 more source

Stiffness dependence of critical exponents of semiflexible polymer chains situated on two-dimensional compact fractals

, 2009
We present an exact and Monte Carlo renormalization group (MCRG) study of semiflexible polymer chains on an infinite family of the plane-filling (PF) fractals. The fractals are compact, that is, their fractal dimension $d_f$ is equal to 2 for all members
C. Vanderzande, Ivan Živić, Sava Milošević, Sunčica Elezović-Hadžić, V. Privman   +4 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

TRADATIONAL FAMILY VALUES AND CONTEMPORARY CHALLENGES OF AZERBAIJANIS [PDF]

مجلة الاجتهاد للدراسات القانونية والاقتصادية, 2019
Under conditions of globalization traditional moral values in the modern Azerbaijani family are subjected to change. The characteristic of a family's activity, which is a complicated social phenomenon, is determined by a number of different conditions ...
Dr. Nuruzade sahla
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Testing the Efficacy of Family Health-Model of REBT on Family Values and Quality of Family Life Among Parents of Children with Visual Impairment. [PDF]

J Ration Emot Cogn Behav Ther, 2022
Ede MO, Okeke CI, Chinweuba NH, Onah SO, Nwakpadolu GM.   +4 more
europepmc   +1 more source

Family Values and the Regulation of Labor [PDF]

Flexible labor markets require geographically mobile workers to be efficient. Otherwise, firms can take advantage of the immobility of workers and extract monopsony rents. In cultures with strong family ties, moving away from home is costly.
Alesina, Alberto, Algan, Yann, Cahuc, Pierre, Giuliano, Paola   +3 more
core