Results 121 to 130 of about 6,976,149 (315)

Unemployment and well-being in Europe. The effect of country unemployment rate, work ethics and family ties [PDF]

open access: yes
Subjective well-being literature shows that higher unemployment rate corresponds to lower psychological cost of own unemployment. The goal of the paper is to deepen the understanding of this regularity by investigating the role played by the work ethics ...
MIKUCKA Malgorzata
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Falling Through the Cracks: The Impact of Immigration Enforcement on Children Caught Up in the Child Welfare System [PDF]

open access: yes, 2012
This paper outlines the unique challenges that federal and state immigration enforcement measures pose to child well-being and family unity, including the implications for children and families involved in the child welfare ...

core  

Libido-sexual disorders and abandonment of injectable contraceptives among users of the Ivorian Association for Family Well-Being in Korhogo, Côte d'Ivoire. [PDF]

open access: yesFront Glob Womens Health, 2023
Essis EM   +9 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Family Well-Being During the COVID-19 Pandemic: The Risks of Financial Insecurity and Coping. [PDF]

open access: yesJ Res Adolesc, 2023
Gonzalez MR   +15 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Relationship Between Family Environment, Parenting Styles and Adolescents’ Well-Being in Cameroon [PDF]

open access: yes, 2007
The main objective of this thesis was to explore the relationship between family environment, parenting styles and adolescents’ well-being in a sample of Cameroonian adolescents.
Mohamadou, Galy
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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