Results 81 to 90 of about 15,396 (232)

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

Journal of Applied Toxicology, Volume 45, Issue 12, Page 2641-2653, December 2025.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto, Shota Yanagida, Shotaro Uehara, Hiroshi Suemizu, Yasunari Kanda, Hiroyuki Kawagishi   +7 more
wiley   +1 more source

Dynamic interactions of a conserved enterotoxigenic Escherichia coli adhesin with intestinal mucins govern epithelium engagement and toxin delivery [PDF]

, 2016
At present, there is no vaccine for enterotoxigenic Escherichia coli (ETEC), an important cause of diarrheal illness. Nevertheless, recent microbial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to its ...
Bhullar, Kirandeep, Fleckenstein, James M, Kuhlmann, F. Matthew, Kumar, Pardeep, Luo, Qingwei, Vallance, Bruce A, Xia, Lijun, Yang, Hyungjun   +7 more
core   +2 more sources

Management and outcome of a dog with hepatic arteriovenous malformation and extensive thrombosis of splanchnic vessels

Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract This report describes the diagnosis, treatment and long‐term follow‐up of a dog with hepatic arteriovenous malformation and extensive thrombus of the splanchnic vessels. A 1‐year‐old, male, neutered golden retriever presented with haematochezia and ascites.
Yuqing Sun, Alexa Bersenas, Brigitte A. Brisson   +2 more
wiley   +1 more source

Design and evaluation of famotidine mucoadhesive nanoparticles for aspirin induced ulcer treatment

Brazilian Archives of Biology and Technology, 2013
The present study was performed to design and evaluate the famotidine loaded mucoadhesive nanosuspension for aspirin induced ulcer. A 3-factor, 3-level Box-Behnken design was applied to study the effects of amount of the beads (X1), PVPK-30(X2) and Tween-
Dhaval J Patel, Jayvadan K Patel
doaj  

Surgical technique and outcome associated with punch biopsy debridement and primary repair of a proximal duodenal perforation in a red fox

Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract A 4‐year‐old, neutered, male red fox (Vulpes vulpes) was referred for evaluation of a 1‐week history of inappetence and lethargy, unresponsive to outpatient care. Abdominal ultrasound revealed a pyloric linear foreign body extending into the descending duodenum with pneumoperitoneum and peritoneal effusion.
Megan C. Lee, Emma A. Devereux, Josep Aisa   +2 more
wiley   +1 more source

Efficacy and Safety of H2 Blockers as an Add-on Therapy to H1 Antihistamines in Allergic Rhinitis: An Open Label Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Allergic Rhinitis (AR), affecting 10-25% of the global population, is commonly treated with antihistamines and corticosteroids. H2-blockers, when combined with H1 antihistamines, enhance treatment efficacy and reduce symptoms. There
Prasenjit Das, Debasis Ray, Biplab Nath, Shanta Sutradhar   +3 more
doaj   +1 more source

Influence of rabeprazole and famotidine on pharmacodynamic profile of dual antiplatelet therapy in clopidogrel-sensitive patients: The randomized, prospective, PROTECT trial

Platelets, 2020
Although acid suppressants are needed to attenuate gastrointestinal bleeding (GIB) after percutaneous coronary intervention (PCI), pharmacodynamic interaction between clopidogrel and proton pump inhibitor (PPI) can increase the risk of high platelet ...
Jong-Hwa Ahn, Yongwhi Park, Jae Seok Bae, Jeong Yoon Jang, Kye-Hwan Kim, Min Gyu Kang, Jin-Sin Koh, Jeong Rang Park, Seok-Jae Hwang, Choong Hwan Kwak, Jin-Yong Hwang, Young-Hoon Jeong   +11 more
doaj   +1 more source

Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition [PDF]

, 2018
Following a myocardial infarction (MI), the immune system helps to repair ischaemic damage and restore tissue integrity, but excessive inflammation has been implicated in adverse cardiac remodelling and development towards heart failure (HF).
Cleland, John G.F., Harding, Sian E., Hasham, Muneer G., Khan, Habib, Panahi, Mona, Papanikolaou, Angelos, Rosenthal, Nadia A., Sattler, Susanne, Torabi, Azam, Vazir, Ali, Zhang, Ji-Gang   +10 more
core   +2 more sources

Ivermectin, Famotidine, and Doxycycline: A Suggested Combinatorial Therapeutic for the Treatment of COVID-19 [PDF]

, 2020
Parth Sarthi Sen Gupta, Malay Kumar Rana
openalex   +1 more source

Pembuatan Sediaan Tablet Mengapung Famotidin Menggunakan Kompleks Polielektrolit Kitosan-Pektin Sebagai Bahan Matriks [PDF]

, 2011
Floating tablet is one of the drug delivery system retained in the stomach which aims to prolong the lag time of the drug in the stomach. This principle can be used to improve the efficacy of famotidine in treating diseases in the stomach The purpose of ...
Anwar, E. (Effionora), Sagita, E. (Erny), Surini, S. (Silvia)   +2 more
core