Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Review of The Mind’s I by Douglas Hofstadter and Daniel Dennett (1981) (review revised 2019 [PDF]
, 2019 A mixed bag dominated by H & D's reductionist nonsense. This is a follow-up to Hofstadter´s famous (or infamous as I would now say, considering its unrelenting nonsense) Godel, Escher, Bach (1980).
Starks, Michael
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fifty two years ago in Jerusalem
, 2013 Short information about the conference in 1960 in Jerusalem is presented together with an interesting photo where we can find several famous mathematicians participated in this conference.
Maligranda, Lech
core +1 more source
Court of Appeal found no love for Topshop tank: the image right that dare not speak its name [PDF]
, 2015 This article contains an analysis of the first instance and appeal decisions of the "Rihanna" case. In particular, the authors consider the substantive law of passing off in the context of the unauthorised use of a celebrity’s image on a Topshop tank ...
Fletcher, Susan Emma, Mitchell, Justine
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
\u3cem\u3eBaptiste v. de Volunbrun 5 H. & J. 86 (Md 1820)\u3c/em\u3e: the Events Surrounding an Early Nineteenth-Century Freedom Petition Before the Maryland Court of Appeals [PDF]
, 2012 BAPTISTE V. DE VOLUNBRUN 5 H. & J. 86 (Md. 1820): In Jean Baptiste’s 1820 freedom petition we have not only a slavery case typical of the region and period, but also a compelling and informative narrative from the beginning of the end of North America’s ...
Ellerbe, Kurt
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Rising Stars, Superstars and Dying Stars: Hedonic Explorations of Autograph Prices [PDF]
Key studies have explored the economics of rising stars, superstars and ‘has beens’, but relatively little economic literature exists on the associated parallel memorabilia markets.
Alan Collins +2 more
core
A collection of color slides of Europe as a teaching instrument for economic geography [PDF]
, 1955 Thesis (Ed.M.)--Boston ...
Caruso, Evelyn Marie
core +1 more source