Results 51 to 60 of about 963,670 (283)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
FRAU ANNA’S INTERIOR MONOLOGUE IN STRATIS TSIRKAS’ DRIFTING CITIES [PDF]
The present paper aims at analyzing the direct interior monologue of one of the main characters in Stratis Tsirkas’ novel Drifting Cities , Frau Anna, starting both from Dorrit Cohn’s and Gerard Genette’s main assumptions on how consciousness is (re ...
Daniela STOICA, Elona BIBA-ÇEÇE
doaj
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Near-Stall Modelling of a Pitching Airfoil at High Incidence, Mach Number and Reduced Frequency
The prediction accuracy of aeroelastic stability in fans and compressors depends crucially on the accuracy of the underlying aerodynamic predictions. The prevalent approach in the field solves the unsteady Reynolds-averaged Navier—Stokes equations in the
Christoph Brandstetter, Sina Stapelfeldt
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Considerando-se que o sobrepeso e obesidade representam uma realidade no contexto mundial e, inclusive, local, o que tem propiciado um crescimento das produções científicas sobre o referido tema, esta pesquisa procedeu à investigação acerca da ...
Fábio Thomaz Melo +3 more
doaj +2 more sources
UHBR Open-Test-Case Fan ECL5/CATANA
The application of composite fans enables disruptive design possibilities but increases sensitivity to multi-physical resonance between aerodynamic, structure dynamic and acoustic phenomena.
Valdo Pagès +6 more
doaj +1 more source
An embedding of the Cantor fan into the Lelek fan
The Lelek fan $L$ is usually constructed as a subcontinuum of the Cantor fan in such a way that the set of the end-points of $L$ is dense in $L$. It easily follows that the Lelek fan is embeddable into the Cantor fan. {It is also a well-known fact that the Cantor fan is embeddable into the Lelek fan, but this is less obvious.
Banič, Iztok +2 more
openaire +4 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Exergy-Based Efficiency Assessment of Fans vs. Isentropic Efficiency
The efficiency definition allows us to compare two machines with each other. In general, the efficiency is defined as the ratio of usable power to the required power. This raises the question: what is the usable power?
Johannes Brötz +2 more
doaj +1 more source

